Histone-complexed Dna Levels Are Associated with Coagulopathy, Inflammation and Endothelial Damage Early after Pediatric Trauma
نویسندگان
چکیده
Introduction: The release of damage-associated molecular pattern molecules (DAMPs) after injury has been suggested to activate innate immunity and may form a key link between inflammation and coagulation in trauma. We aimed to study the presence of circulating DAMPs in the form of histone-complexed DNA (hcDNA) in our pediatric trauma population and investigated the association between hcDNA, trauma induced coagulopathy, inflammation and endothelial damage.
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تاریخ انتشار 2015